Nutritional Information. Answers to questions about nutrition, obesity, herbal and nutritional supplements, and the role of diet in improving and maintaining your health.
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Scientists reveal what seven days of fasting does to the human body
Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually inspire treatments that mimic its effects.
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Diet drinks work as well as water for weight loss, major trial finds
A two-year randomized clinical trial involving 493 adults with overweight or obesity found that diet soft drinks were essentially as effective as water for long-term weight loss and weight maintenance. Participants drinking beverages sweetened with aspartame, acesulfame-K, or sucralose lost a similar amount of weight to those drinking water, while both groups also saw improvements in waist size, body composition, and several metabolic measures.
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Leucine does more than build muscle. It powers up your cells
The essential amino acid leucine can boost cellular energy production by protecting key proteins on mitochondria from being destroyed. The discovery reveals a new connection between nutrition and metabolism that could eventually lead to new approaches for metabolic disorders and cancer.
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This diet may slow brain aging by 2.5 years
People who followed the MIND diet more closely showed slower brain shrinkage and less grey matter loss over time, with the strongest differences equivalent to about 2.5 years of delayed brain aging. Berries and poultry were linked with healthier brain changes, while sweets and fried fast foods were associated with greater tissue loss.
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Vitamin D drug may help crack pancreatic cancer’s protective shield
A vitamin D analog may help break down pancreatic cancer’s protective defenses, potentially making tumors more vulnerable to chemotherapy and immune attack. A small clinical trial found encouraging responses, especially in patients whose tumors had high levels of the vitamin D receptor.
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Your gut may be making a molecule that raises Alzheimer’s risk
Scientists have linked a gut bacterial compound called ImP to greater Alzheimer’s risk, harmful brain protein buildup, and faster cognitive decline. The finding raises the possibility that reducing ImP in the blood could one day help slow or prevent dementia.
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Vitamin C linked to fewer deaths in blood disorder trial
Vitamin C may do more than support the immune system. In a phase 2 trial of people with precancerous or low risk blood cancers, daily vitamin C did not slow abnormal cell growth, but it was linked to favorable changes in inflammation and fewer serious complications. An exploratory follow up also found fewer deaths among participants taking vitamin C than among those receiving placebo.
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Could quitting ultra-processed food boost your mental health?
People with depression who dramatically cut ultra-processed foods experienced notable improvements in their symptoms in a small preliminary study. Researchers suspect healthier eating may benefit the brain partly by reducing gut damage and chronic inflammation.
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Mulberry may reshape gut bacteria and influence metabolism
Mulberry compounds may reshape the gut microbiome in ways that support intestinal health and metabolism, with some combinations showing especially strong effects in animal studies. However, the results vary depending on the plant part and processing method, and the benefits have yet to be confirmed in humans.
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Creatine may help build muscle even without exercise, researchers find
Creatine helped middle-aged adults gain muscle and strength even without a structured workout program in a new 12-week study. When combined with exercise and a calorie-reduced diet, it produced even greater strength gains while helping participants add lean tissue and lose fat. Researchers say the results strengthen the case for creatine as a potentially useful tool for maintaining muscle with age.
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Scientists just discovered what coffee really does to your gut and brain
A new study suggests coffee may influence mood and brain function by changing the activity of microbes in the gut. Both caffeinated and decaf coffee were linked to lower stress, depression, and impulsivity, while also producing measurable changes in gut bacteria and metabolites. Decaf was associated with better learning and memory, while caffeinated coffee appeared to reduce anxiety and improve attention.
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Zepbound and Mounjaro may turn on the body’s calorie-burning brown fat
Tirzepatide, sold as Mounjaro and Zepbound, activated calorie-burning brown fat in obese mice, revealing a potential metabolic effect beyond appetite suppression. If confirmed in humans, the finding could help explain the drug’s powerful benefits and inspire more comprehensive treatments for obesity and diabetes.
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Pomegranate compound improves heart function by up to 80% in study
A compound the body can make after eating pomegranates, walnuts, and some berries improved measures of heart function by up to 80% in animal models of a difficult-to-treat form of heart failure. Urolithin A helped stiff heart tissue relax and reduced scarring and abnormal enlargement. It also improved relaxation in engineered human heart tissue.